Biopolym. Cell. 2016; 32(2):83-97.
Огляди
Хітозан-апатитні композити: синтез і властивості
- Сумський державний університет
вул. Римського-Корсакова, 2, Суми, Україна, 40007 - Інститут мікробіології та імунології ім. І. І. Мечникова НАМН
вул. Пушкінська, 14, Харків, Україна, 61057
Abstract
Мета цього короткого огляду – розгляд застосування унікального біополімеру хітозану в практичній медицині, особливо для інженерії кісткової тканини. Основне місце в статті відведено синтезу та властивостям інноваційних біоматеріалів на основі хітозану, таким як CaP-хітозан (CS-CP)-композити і хітозан-альгінатні (CS-AG)-скаффолди. У статті висвітлено фізико-хімічні властивості, спектральні характеристики і хімічні модифікації молекули хітозану. Отримані хітозан-апатитні композитні матеріали були проаналізовані з використанням методу рентгенівської дифракції для аналізу кристалічної природи їх структур. Було виявлено, що додавання хітозану до композитного матеріалу призводить до зниження кристалічності вихідного апатиту. Крім того, акцентовано увагу на антибактеріальні властивості хітозану, використанні наночастинок хітозану для отримання нановолокон і створенні системи контрольованої доставки ліків.
Keywords: хітозан, гідроксиапатит, біокомпозити, рентгенівська дифракція
Повний текст: (PDF, англійською)
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