Biopolym. Cell. 2012; 28(3):181-189 .
Огляди
Гени мікроцефалії (огляд)
- Інститут біохімії і біотехнології, Университета Пенждаба
Лахор, Пакистан
Abstract
В огляді узагальнено дані останніх років з вивчення генів мікроцефалії. Обговорюються результати молекулярно-генетичного
дослідження цих генів, зроблено оцінку семи визначених локусів
(MCPH1–MCPH7), описано відповідні їм гени і білкові продукти
генів, їхня можлива роль у нормальному розвитку мозку, а також
мутації у цих генах.
Keywords: мікроцефалія, локус MCPH, ген MCPH, мутація, нейрогенез
Повний текст: (PDF, англійською)
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