Кальдесмон і кальпонін – білки тонкого філаменту гладеньких м\'язів: структура та механізми функціонування

Данилова, В. М.; Куликова, Н. В.

doi:10.7124/bc.00040E

Biopolym. Cell. 1996; 12(1):16-28.

http://dx.doi.org/10.7124/bc.00040E

Кальдесмон і кальпонін – білки тонкого філаменту гладеньких м'язів: структура та механізми функціонування

1Данилова В. М., 1Куликова Н. В.

НДІ фізіології ім. академіка Петра Богача
Київського національного університету імені Тараса Шевченка
Проспект Академіка Глушкова, 2, Київ, Україна, 03187

Abstract

У представленому огляді описано структуру, деякі властивості та механізми функціонування двох нещодавно відкритих білків – кальдесмону та кальпоніну. Обидва білки розташовані на актиновому філаменті, взаємодіють з тропоміозином та Ca²⁺ -зв'язуючими білками і здатні Ca²⁺ -залежним способом регулювати взаємодію міозину з актином. Регуляторна активність кальдесмону і кальпоніну може модулюватися шляхом фосфорилювання.

Повний текст: (PDF, українською)

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