Biopolym. Cell. 1996; 12(1):16-28.
Caldesmon and calponin – the thin filamentassociated proteins of smooth muscle: structure and mechanisms of functioning
- Petr Bogach Institute of Physiology
Taras Shevchenko National University of Kyiv
2, Academika Glushkova Ave Str., Kyiv, Ukraine, 03187
Abstract
The structure and properties of two novel smooth muscle regulatory proteins associated with thin filament arereviewed. A detailed description of the «heavy» caldes man isofarm and of the localization of ca Ides man interaction sites withactin, calmodulin, tropomyosin and myosin are given. Current conceptions concerning the mechanism ofcaldcsmon and calponin function during regulation of myosin interaction with actin are considered.
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