Biopolym. Cell. 1995; 11(1):5-19.
Генетичні наслідки дії
іонізуючого опромінення в низьких дозах
на репродуктивну функцію організму миші
1Століна М. Р., 1Соломко О. П.
- Інститут молекулярної біології і генетики НАН України
Київ, Україна
Abstract
В огляді розглянуто опубліковані дослідження, пов'язані із впливом малих доз іонізу
ючого випромінення на репродуктивну функцію організму мишей різних генотипів. Аналіз смбріогенетичних даних, які отримано на мишах як в модельних експериментах з малими дозами радіації, так і в 30-км зоні ЧАЕС, дозволив зробити висновок про те,
що генотоксичний ефект реалізується на рівні дестабілізації геному статевих та соматичних клітин зародків і дорослих тварин. Наслідками каріотипічної нестабільності
часто є різноманітні генетичні аномалії, які ведуть до зниження репродуктивної функції тварин і зростання пренатальної загибелі їх нащадків. Обговорюються перспективні
напрями вивчення віддалених генетичних наслідків хронічної дії іонізуючих випромінень в малих дозах на організм ссавців.
Повний текст: (PDF, українською)
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