Biopolym. Cell. 1989; 5(3):23-38.
http://dx.doi.org/10.7124/bc.0000B4
Огляди
Вуглецева катаболітна інактивація у дріжджів – важливий спосіб регуляції на посттрансляційному рівні
1Титоренко В. І., 1Сибірний А. А.
  1. Львівське відділення, Інститут біохімії ім. О. В. Палладіна АН УРСР
    Львів, СРСР

Abstract

В огляді узагальнено основні закономірності функціонування в дріжджових клітинах вуглецевої катаболітної інактивації. Запропоновано нову інтерпретацію фізіологічного сенсу цього регуляторного механізму. Представлено дані про роль сАМР, протеїнкіназ і вакуолярних протеїназ у регуляції вуглецевої катаболітної інактивації у дріжджів Saccharomyces cerevisiae і метилотрофних дріжджів. Описано унікальний механізм деградативної інактивації, що діє у метилотрофних дріжджів і пов’язаний зі «злиттям» пероксисом з вакуолями з подальшою деградацією пероксисомних ферментів. Відзначено, що генетичний контроль вуглецевої катаболітної інактивації, а також молекулярні механізми цього процесу для більшості ферментів не вивчені
Повний текст: (PDF, російською)

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