Взаємодія полімерів групи полігідроксиалканоатів з клітинами і тканинами

Майбородін, І. В.; Кузнецова, І. В.; Шевела, А. І.; Манаєв, А. О.; Частикін, Г. А.

doi:10.7124/bc.0008A0

Biopolym. Cell. 2014; 30(4):273-278.

http://dx.doi.org/10.7124/bc.0008A0

Огляди

Взаємодія полімерів групи полігідроксиалканоатів з клітинами і тканинами

1Майбородін І. В., 1Кузнецова І. В., 1Шевела А. І., 1Манаєв А. О., 1Частикін Г. А.

Центр нових медичних технологій
Інститут хімічної біології і фундаментальної медицини СО РАН
пр. ак. Лаврентьєва, 8, Новосибірськ, Російська Федерація, 630090

Abstract

У літературі останніх років, присвяченій результатам вивчення, отримання і застосування полігідроксиалканоатів (ПГА), міститься безліч експериментальних і клінічних даних щодо ефективності і безпеки використання цих полімерів для медико-біологічних потреб. Проте застосування ПГА як самостійно, так і в комбінації з іншими препаратами і речовинами, поза сумнівом, повинно мати свої переваги і свої недоліки. Варто відмітити повну відсутність у науковій літературі відомостей про протипоказання і ускладнення за використання ПГА, а також недостатню кількість даних стосовно закономірностей деградації ПГА у живому організмі і морфологічних процесах, з цим пов’язаних.

Keywords: полігідроксиалканоати, реконструктивна медицина, біодеградація, клітинні технології

Повний текст: (PDF, російською) (PDF, англійською)

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