Biopolym. Cell. 2014; 30(1):10-15.
Огляди
Нові аспекти агрегації тромбоцитів
1Рока-Мойя Я. М., 1Білоус В. Л., 1Жерносєков Д. Д., 1Гриненко Т. В.
  1. Інститут біохімії ім. О. В. Палладіна НАН України
    вул. Леонтовича, 9, Київ, Україна, 01601

Abstract

Відомо, що агрегація тромбоцитів – це важливий процес, який лежить в основі утворення гемостатичної пробки та формування тромба. Однак останні дослідження показали, що тромбоцитарна агрегація є значно складнішим і динамічнішим процесом, ніж вважали раніше. Існує декілька механізмів, які ініціюють агрегацію тромбоцитів, і кожен із них реалізується за певних умов in vivo. У той же час необхідно враховувати вплив на цей процес окремих білків плазми крові. Мета даного огляду – узагальнити сучасні дані, присвячені адгезивним молекулам та їхнім рецепторам, які забезпечують тромбоцитарну агрегацію за різних умов.
Keywords: агрегація тромбоцитів, адгезивні молекули

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