Biopolym. Cell. 2010; 26(6):441-449.
http://dx.doi.org/10.7124/bc.000173
Огляди
Взаємодія бакуловiрусів з клітинами хребетних у системі in vitro
1Соломко О. П., 1Захарук О. А., 1Чащина Л. І., 1Строковська Л. І.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

Проаналізовано дані літератури стосовно вивчення нової векторної системи для клітин хребетних, заснованої на вірусах комах – бакуловірусах. Розглядаються шляхи та механізми проникнення рекомбінантних бакуловирусів у клітини, фактори, що впливають на ефективність трансдукції, принципи модифікації вірусного дисплея, реакція різних типів клітин на вбудовування вірусу. Обговорюються перспективи використання рекомбінантних бакуловірусів у клітинній інженерії.
Keywords: бакуловірус, хребетні, взаємодія, трансдукція, дисплей, клітинна відповідь
Повний текст: (PDF, російською)

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