Biopolym. Cell. 2010; 26(3):163-174.
http://dx.doi.org/10.7124/bc.000153
Огляди
Клітинний цикл і епігенетичні зміни ДНК у рослин
1Шевченко Г. В.
  1. Інститут ботаніки ім. М. Г. Холодного НАН України
    вул. Терещенківська, 2, Київ, Україна, 01601

Abstract

Щоб мінімізувати вплив довкілля рослини використовують декілька стратегій. Одна з них – це наслідування модифікацій генної експресії, які відбуваються без зміни послідовності нуклеотидів ДНК (епігенетика). Сигнальний шлях Rb-E2F/DP (ретинобластома (Rb)–транскрипційнi фактори E2F/DP) поєднує клітинний цикл з факторами модифікації ДНК і хроматину та координує проліферацію і диференціацію клітин залежно від зовнішнього впливу. В огляді систематизовано дані щодо активності сигнального шляху Rb-E2F/DP і його зв’язку з епігенетичними змінами ДНК у рослин.
Keywords: ДНК, транскрипційний фактор E2F, комплекси, що ремодулюють хроматин, епігенетика
Повний текст: (PDF, російською) (PDF, англійською)

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