Biopolym. Cell. 2005; 21(3):220-229.
http://dx.doi.org/10.7124/bc.0006EC
Огляди
Асоційовані з пухлиною антигени та розвиток імунотерапевтичних стратегій
1Кіямова Р. Г., 1Філоненко В. В.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

Зроблено огляд асоційованих з пухлиною антигенів, методів їхньої ідентифікації та існуючих на сьогодні імунотерапев­тичних стратегій щодо лікування раку. Особливу увагу приді­лено антигенам, ідентифікованим з використанням методо­логії SEREX (серологчіна ідентифікація антигенів за допомо­гою рекомбінантно експресованих клонів) та наведено кате­горії асоційованих з пухлиною антигенів (у тому числі, ідентифікованих із застосуванням SEREX). Класифіковано головні імунотерапевтичні підходи та описано успіхи актив­ної специфічної імунотерапії за допомогою імунодомінантних пептидів асоційованих з пухлиною антигенів
Keywords: імунотерапія, антиген, рак
Повний текст: (PDF, англійською)

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