Biopolym. Cell. 2005; 21(3):187-219.
http://dx.doi.org/10.7124/bc.0006EB
Огляди
Генетичний і епігенетичний контроль росту і розвитку рослин. Молекулярно-генетичний контроль проведення і реалізації сигналів ауксинів
1Циганкова В. А., 1Галкіна Л. А., 1Мусатенко Л. І., 1Ситник К. М.
  1. Інститут біоорганічної хімії та нафтохімії НАН України
    вул. Мурманська, 1, Київ, Україна, 02094
  2. Інститут ботаніки ім. М. Г. Холодного НАН України
    вул. Терещенківська, 2, Київ, Україна, 01601

Abstract

Представлено дані щодо регуляторних компонентів сигналь­ного шляху індоліл-3-оцтової кислоти (ЮК) у клітинах рос­лин: мембранні білки-рецептори, які сприймають екзогенні сигнали ІОК, систему вторинних месенджерів (cAMP, cGMP, інозитолтрифосфат і діацил^ліцерол, цитоплазматичний ка­льцій, «сенсорний» білок Са2+ сигналів – кальмодулін), що опосередковують передачу сигналів ІОК з рецепторів на ефектори (ферменти), які каталізують процеси внутрішньоклітинного метаболізму. Подано перелік ідентифікованих в ос­танні роки генів, які детермінують синтез білків, що беруть участь у проведенні сигналів ІОК у Arabidopsis: ген АВР1, який кодує мембранний білок – рецептор ІОК; AtCPl і AtCBLl гени, що кодують «сенсорні» білки Са2+ ; численні родини MDR генів мембранних білків, які беруть участь в активному АТР-залежному транспорті протонної форми ІОК через мем­брани клітин, PIN генів білків, що контролюють пасивний полярний внутрішньо- і міжклітинний транспорт аніонної форми ІОК, ARG1 і RCN1 генів білків, які відповідальні за передавання гравітропічних сигналів і регулюють полярний транспорт аніонної форми ІОК через мембрани спеціалі­зованих гравічутливих клітин — статоцитів, VTI генів SNA­RE білків, що беруть участь у везикулярному внутрішньо­клітинному транспорті ІОК, і AtMRP5 гена білка — транс­портера кон'югованих форм ІОК; ARF генів трансфакторів, шр активуються ауксином і контролюють експресію ранніх ауксин-регульованих Aux/IAA, SAUR, GH3 і ACS генів, а також численні родини SKP1, RBX1, ATCUL1, ASKI, ASK2, AXR1, ECR1, RCEI, ENR2p, Cdc4p, Cdc53p, Scplp, TIRI генів білків (членів убіквітин-протеїнлігазного комплексу) і CSN генів білків (членів мультисубодиничного білкового регулятор­ного комплексу СОР9 сигналосоми) — компонентів убіквітин/протеасомо-опосередкованого шляху деградації Аих/ІАА білків, що пригнічують проведення сигналів ауксину. Розгляну­ то гіпотетичну модель регуляції ІОК експресії генів.
Keywords: рецептори індоліл-3-оцтової кислоти (ІОК), вторинні мессенджери ІОК, білки — транспортери ІОК, ауксин-регульовані гени, убіквитин-протеасомний шлях деградації білків — репресорів ІОК
Повний текст: (PDF, російською)

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