Biopolym. Cell. 2005; 21(1):3-11.
Огляди
Молекулярно-генетичні механізми нейроонтогенезу
1Цимбалюк В. І., 1Семенова В. М., 1Медведев В. В.
- Інститут нейрохірургії ім. академіка А. П. Ромоданова АМН України
вул. Мануїльського, 32, Київ, Україна, 04050
Abstract
На грунті літературних даних представлено сучасні уявлення щодо молекулярно-генетичних
механізмів нейроонтогенетичних процесів, запропоновано схематичне трактування поступової
диференціації нейрональної клітини у ході ускладнення топології міжнейронних зв'язків, а також
наведено відомості стосовно онтогенетичної ролі нейрональних стовбурових прогеніторів та
розглянуто можливість вивчення топологічних перебудов нейрональних ансамблів під час генерування енграм пам'яті з точки зору мікроембріональних процесів.
Keywords: нейрональна індукція, сигнальна трансдукція, генетична експресія, гомеодоменні
фактори транскрипції, диференціація і детермінація, фактори росту, нейрогенна стовбурова клітина.
Повний текст: (PDF, українською)
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