Biopolym. Cell. 2003; 19(6):492-498.
Структура та функції біополімерів
Модель тривимірної структури основної антигенної детермінанти білка gp120 HIVThaiIand
1Андріанов А. М.
  1. Інститут біоорганічної хімії НАН Білорусі
    вул. Академіка В. Ф. Купревича, 5, корп.2, Мінськ, Республіка Білорусь, 220141

Abstract

З використанням даних спектроскопії ЯМР, опублікованих у літератури побудовано модель тривимірної структури основ­ної антигенної детермінанти білка gp120 HIVThailand. Визначе­но елементи її вторинної структури і конформації нерегуляр­них сегментів. Досліджено конформаційні можливості фрагмента, який формує імунодомінантний епітоп вірусу. Отри­мані результати обговорюються разом з відомими даними щодо просторової організації гомологічної ділянки білка gp120 HIVMN

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