Biopolym. Cell. 2003; 19(4):328-349.
Дискусії
Наша «шагренева шкіра» — це наша проблема. Нам її і вирішувати. 2. Єдиний сполучений простір органзіму
1Кордюм В. А.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

Організм є особливим, єдиним у собі самому утворенням, що складається з дуже великої кількості різних клітин. Ана­лізується проблема такої єдності. Висувається і обгрунтовується положення щодо деякого єдиного простору організму у вигляді наступних сполучених просторів: безперервного від­ критого регуляторно-метаболічного, безперервного закритого регуляторно-метаболічного, ротаційного, архітектурного і динамічного. Обговорюються особливості такого поєднання і наслідки, які випливають з цього для проблеми, що розгля­дається.

References

[1] Gumbiner BM. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 1996;84(3):345-57.
[2] Schuppan D, Ruhl M. Matrix in signal transduction and growth factor modulation: «SIMED 94» 3rd Braz. Symp. Estracell. Matrix (Angra dos Reis, Sept. 11-14, 1994). Braz J Med Biol Res. 1994; 27(9): 2125-41.
[3] Kordyum VA. Our "Shagreen leather" is our problem. And we have to solve it. Biopolym Cell. 2003; 19(2):113-32.
[4] Nakamura J, Swenberg JA. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res. 1999;59(11):2522-6.
[5] Brosius J. Most of the 98,5 % non-coding genomic DNA in mammals are retroposon-derived: genomic desert or repertoirei: The 12th Conversation in Biomolecular Stereodynaraics (Albany,2001). J Biomol Struct Dyn. 2001; 18(6): 932.
[6] Rubin GM. The draft sequences. Comparing species. Nature. 2001;409(6822):820-1.
[7] Bossier BL. Tiny conspiracies. Nat Hist. 2001; 110(4): 16-18; 20-22.
[8] Broda E. The Evolution of Bioenergetic Processes, Pergamon, Oxford, 1975. 220 p.
[9] Kordyum VA. What are our "garbage", its scavenging and the consequences of this phenomenon. Biopolym Cell. 2002; 18(6):457-66.
[10] Karrer HE. The striated musculature of blood vessels. II. Cell interconnections and cell surface. J Biophys Biochem Cytol. 1960;8:135-50.
[11] Falk MM. Biosynthesis and structural composition of gap junction intercellular membrane channels. Eur J Cell Biol. 2000;79(8):564-74.
[12] Larsen WJ. Structural diversity of gap junctions. A review. Tissue Cell. 1977;9(3):373-94.
[13] Finbow M. Bridges between the body's cells. New Sci. 1981. 89(1234): 24-27.
[14] White TW, Paul DL. Genetic diseases and gene knockouts reveal diverse connexin functions. Annu Rev Physiol. 1999;61:283-310.
[15] Hertzberg EL, Spray DC, Bennett MVL. An antibody to gap junctions blocks gap junctional conductance. J Cell Biol. 1984; (4, pt 2): 343.
[16] Kristian Enkvist MO, McCarthy KD. Astroglial Gap Junction Communication Is Increased by Treatment with Either Glutamate or High K+ Concentration. J Neurochem. 1994;62(2):489–95.
[17] Opsahl H, Rivedal E. Quantitative Determination of Gap Junction Intercellular Communication by Scrape Loading and Image Analysis. Cell Commun Adhes. 2000;7(5):367–75.
[18] Bennett MVL, Spray DC, White RL. Gap junctions as excitable membranes. J Cell Biol. 1983; 97(5, pt 2): 124.
[19] Brightman MW, Tao-Cheng JH. Cell membrane interactions between astrocytes and brain endothelium. Biochem. Patrol. Astrocytes: Proc. Satell. Symp Int Soc Neurochem Am Soc Neurochem. (Miami, Fla, May 26-29, 1987). New York, 1988: 21-39.
[20] Olsen I, Hand C, Muir H. Cell-to-cell transfer of lysosomal enzymes from lymphocytes to I-cell disease fibroblasts. Biochem Soc Trans. 1987; 15(3):446—447.
[21] Haimes H, Dubertret L, Bell E. Melanocytes transfer melanosomes to keratinocytes in skin equivalent model in vitro. J Cell Biol. 1985;101(5, pt 2): 373.
[22] Garcia-Dorado D, Ruiz-Meana M, Padilla F, Rodriguez-Sinovas A, Mirabet M. Gap junction-mediated intercellular communication in ischemic preconditioning. Cardiovasc Res. 2002; 55(30: 456-65.
[23] Giepmans BN, Hengeveld T, Postma FR, Moolenaar WH. Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication. J Biol Chem. 2001;276(11):8544-9.
[24] Yao J, Morioka T, Li B, Oite T. Coordination of mesangial cell contraction by gap junction--mediated intercellular Ca(2+) wave. J Am Soc Nephrol. 2002;13(8):2018-26.
[25] Bannerman P, Nichols W, Puhalla S, Oliver T, Berman M, Pleasure D. Early migratory rat neural crest cells express functional gap junctions: evidence that neural crest cell survival requires gap junction function. J Neurosci Res. 2000;61(6):605-15.
[26] Fick J, Barker FG 2nd, Dazin P, Westphale EM, Beyer EC, Israel MA. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci U S A. 1995;92(24):11071-5.
[27] Mac Donald C. Genetic analysis of junctional transfer. Eur J Cell Biol. 1983; (Suppl. 1):26.
[28] Vitkauskas G, Kole J, Canellakis ES. Biochemical assay of inhibitors of metabolic cooperation. Exp Cell Res. 1983;145(1):15-30.
[29] Dean MF, Diment S. Exchange of lysosomal enzymes between cells. Biochem Soc Trans. 1984;12(3):524-6.
[30] Fletdwr WJ, Tuso PJ, Greenan JRT. Gap junction mediation of hormone action that causes camp-dependent protein kinase dissociation in ovarian granulose cells. J Cell Biol. 1983; 97(5, pt 2): 80.
[31] Nanno M, Hata M, Doi H, Satomi S, Yagi H, Sakata T, Suzuki R, Itoh T. Stimulation of in vitro hematopoiesis by a murine fetal hepatocyte clone through cell-cell contact. J Cell Physiol. 1994;160(3):445-54.
[32] Tonna EA. Disruption of cellular communication and bone surface regulation during skeletal aging. 12t h Int. Congr. Gerontol. (Hamburg, July 12—17, 1981): Abstr.—Hamburg, 1981:122.
[33] Hiroshi Yamasaki. Gap junctional intercellular communication and carcinogenesis. Carcinogenesis. 1990; 11(7): 1051-8.
[34] Carlson CD, Tank AW. Increased cell-cell contact stimulates the transcription rate of the tyrosine hydroxylase gene in rat pheochromocytoma PC18 cells. J Neurochem. 1994;62(3):844-53.
[35] Pitts ID, Fibow ME. The functional integration of cells in animal tissues: 5th Symp Br Soc Cell Biol. Cambridge: Univ. press, 1982. 360 p.
[36] Blennerhassett MG, Caveney S. How selective is gap junctional permeability at the compartment borderi. J Cell Biol. 1983; 97(5, pt 2): 125.
[37] Olsen I, Dean MF, Muir H, Fenson A. Direct enzyme transfer from lymphocytes to fibroblasts. J Cell Biol. 1983; Suppl. 1:32.
[38] Dean MF, Rodman J, Levy M, Stahl P. Contact formation and transfer of mannose BSA gold from macrophages to cocultured fibroblasts. Exp Cell Res. 1991;192(2):536-42.
[39] Oviedo-Orta E, Gasque P, Evans WH. Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication. FASEB J. 2001;15(3):768-74.
[40] Nelson PT, Kondziolka D, Wechsler L, Goldstein S, Gebel J, DeCesare S, Elder EM, Zhang PJ, Jacobs A, McGrogan M, Lee VM, Trojanowski JQ. Clonal human (hNT) neuron grafts for stroke therapy: neuropathology in a patient 27 months after implantation. Am J Pathol. 2002;160(4):1201-6.
[41] Son NH, Murray S, Yanovski J, Hodes RJ, Weng N. Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age. J Immunol. 2000;165(3):1191-6.
[42] Weng N. Interplay between telomere length and telomerase in human leukocyte differentiation and aging. J Leukoc Biol. 2001;70(6):861-7.
[43] Blau HM, Brazelton TR, Weimann JM. The evolving concept of a stem cell: entity or function? Cell. 2001;105(7):829-41.
[44] Gunsilius E, Gastl G, Petzer AL. Hematopoietic stem cells. Biomed Pharmacother. 2001;55(4):186-94.
[45] Labat ML, Pouchelet M, Gouhier N, Boireau P, Milhaud G. Regulation by phagic T-lymphocytes of a (pluripotent?) organ stem cell present in adult human blood. A beneficial exception to self-tolerance. Biomed Pharmacother. 2001;55(2):79-90.
[46] Cervantes RB, Stringer JR, Shao C, Tischfield JA, Stambrook PJ. Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc Natl Acad Sci U S A. 2002;99(6):3586-90.
[47] Kordyum VA. And then I sat down to write this book: It is not usual notions of human genetics. Kiev, 1993; 248 p.
[48] Save embryonic stem cell research!. Svit Nauky. 2001; 4 (10):18.
[49] Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, Grupp SA, Sieff CA, Mulligan RC, Johnson RP. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med. 1997;3(12):1337-45.
[50] Tokin BP. General Embryology. M.: Vysch Shkola, 1977; 512 p.
[51] Stanyuk I. Human embryology. Bratislava: Veda, 1977. 442 p.
[52] H?kelien AM, Landsverk HB, Robl JM, Sk?lhegg BS, Collas P. Reprogramming fibroblasts to express T-cell functions using cell extracts. Nat Biotechnol. 2002;20(5):460-6.
[53] Landsverk HB, H?kelien AM, K?ntziger T, Robl JM, Sk?lhegg BS, Collas P. Reprogrammed gene expression in a somatic cell-free extract. EMBO Rep. 2002;3(4):384-9.
[54] Berger JJ, Eisenhauer DA, Taylor A. Intracellular protein degradation in cultured bovine lens epithelial cells. In Vitro Cell Dev Biol. 1988;24(10):990-4.