Biopolym. Cell. 2003; 19(3):216-223.
Огляди
Трихотеценові мікотоксини: визначення в об'єктах довкілля
- Інститут біохімії ім. О. В. Палладіна НАН України
вул. Леонтовича, 9, Київ, Україна, 01601 - Національний аграрний університет УААН
вул. Героїв оборони, 15, Київ, Україна, 03041
Abstract
Описано основні методи ідентифікації трихотеценових мікотоксинів, серед яких різні біометоди, тонкошарова хроматографія, газо-рідинна хроматографія, високоефективна рідинна
хроматографія, імуноферментні методи (ELISA), мас-спектрометрія. Розглянуто перспективи розвитку інструментальних методів визначення мікотоксинів на базі використання нових технологічних рішень.
Повний текст: (PDF, російською)
References
[1]
Committee on protection against mycotoxins. Board on Toxicology and Environmental Health Hazards, Commission on Life Sciences, National Research Council. Protection. Against Trichothecene Mycotoxins. Washington: Nat. Acad, press, 1983. 127 p.
[2]
Ciegler A. Mycotoxins: occurrence, chemistry, biological activity. Lloydia. 1975;38(1):21-35.
[3]
Ciegler A, Bennett JW. Mycotoxins and Mycotoxicoses. BioScience. 1980;30(8):512–5.
[4]
Cole RJ, Cox RH. The trichothecenes. Handbook of Toxic Fungal Metabolite. Eds R. J. Cole, R. H. Cox. New York: Acad, press, 1981: 152-263.
[5]
Bamburg JR, Riggs NV, Strong FM. The structures of toxins from two strains of Fusarium tricinctum. Tetrahedron. 1968;24(8):3329-36.
[6]
Sirkisov AKh. Mycotoxicoses. M.: Izd GISHL. 1954; 216 p.
[7]
Bhat VR, Ramakrishna J, Sashidhar RB. Outbreak of mycotoxicosis in Kashmir Valley. Nutr News India. 1989; 10(1):1-3.
[8]
Jim?nez M, Mateo JJ, Mateo R. Determination of type A trichothecenes by high-performance liquid chromatography with coumarin-3-carbonyl chloride derivatisation and fluorescence detection. J Chromatogr A. 2000;870(1-2):473-81.
[9]
Omurtag GZ, Yazicio?lu D. Determination of T-2 toxin in grain and grain products by HPLC and TLC. J Environ Sci Health B. 2000;35(6):797-807.
[10]
Methodological guidelines for determining the toxicity of crops and products affected by fungi of the genus Fusarium sectionSporotrichiella. M: Izd MZ SSSR, 1978; 5 p.
[11]
Wannemacher RW Jr, Bunner DL, Neufeld HA. Toxicity of trichothecenes and other related mycotoxins in laboratory animals. Mycotoxins and Animal Foods. Eds J. E. Smith, R. S. Henderson. Boca Raton: CRC press, 1991. P. 499-552.
[12]
Hayes MA, Schiefer HB. A method for accurate measurement of cutaneous irritancy of trichothecenes. J Environ Pathol Toxicol Oncol. 1990;10(3):103-5.
[13]
Shlosberg AS, Klinger Y, Malkinson MH. Muscovy ducklings, a particularly sensitive avian bioassay for T-2 toxin and diacetoxyscirpenol. Avian Dis. 1986;30(4):820-4.
[14]
Rotter BA, Thompson BK, Prelusky DB, Trenholm HL. Evaluation of potential interactions involving trichothecene mycotoxins using the chick embryotoxicity bioassay. Arch Environ Contam Toxicol. 1991;21(4):621-4.
[15]
Segal R, Milo-Goldzweig I, Joffe AZ, Yagen B. Trichothecene-induced hemolysis. I. The hemolytic activity of T-2 toxin. Toxicol Appl Pharmacol. 1983;70(3):343-9.
[16]
Leal M, Shimada A, Ru?z F, Gonz?lez de Mej?a E. Effect of lycopene on lipid peroxidation and glutathione-dependent enzymes induced by T-2 toxin in vivo. Toxicol Lett. 1999;109(1-2):1-10.
[17]
M?zes M, Barta M, Nagy G. Comparative investigation on the effect of T-2 mycotoxin on lipid peroxidation and antioxidant status in different poultry species. Res Vet Sci. 1999;66(1):19-23.
[18]
Atroshi F, Rizzo A, Sankari S, Biese I, Westermarck T, Veijalainen P. Liver enzyme activities of rats exposed to ochratoxin A and T-2 toxin with antioxidants. Bull Environ Contam Toxicol. 2000;64(4):586-92.
[19]
Shokri F, Heidari M, Gharagozloo S, Ghazi-Khansari M. In vitro inhibitory effects of antioxidants on cytotoxicity of T-2 toxin. Toxicology. 2000;146(2-3):171-6. PubMed PMID: 8167951.
[20]
Rotter BA, Thompson BK, Clarkin S, Owen TC. Rapid colorimetric bioassay for screening of Fusarium mycotoxins. Nat Toxins. 1993;1(5):303-7.
[21]
Thuvander A, Wikman C, Gadhasson I. In vitro exposure of human lymphocytes to trichothecenes: individual variation in sensitivity and effects of combined exposure on lymphocyte function. Food Chem Toxicol. 1999;37(6):639-48. PubMed PMID: 11040865.
[22]
Widestrand J, Lundh T, Pettersson H, Lindberg JE. Cytotoxicity of four trichothecenes evaluated by three colorimetric bioassays. Mycopathologia. 1999;147(3):149-55.
[23]
Methodical instructions for quantification of T-2 toxin in grain and animal feed. Glavnoye upravleniye veterinarii Gosagroproma SSSR. M, 1987. 11 p.
[24]
Boltianskaia EV, Kuvaeva IB, Kroiakova EA. [Screening of yeast strains sensitive to toxin T-2]. Vopr Pitan. 1988;(6):67-8. PubMed PMID: 11122536.
[26]
Madhyastha MS, Marquardt RR, Abramson D. Structure-activity relationships and interactions among trichothecene mycotoxins as assessed by yeast bioassay. Toxicon. 1994;32(9):1147-52.
[27]
Kotik AN, Trufanova VA. Determination of trichothecene mycotoxins in feed and fungal culture method bioavtograficheskim. Tr Vsesoyuz in-ta zerna i produktov yego pererabotki. 1987;65:127-30.
[28]
Kotik AN, Trufanova VA. [A bioautographic method of analyzing trichothecene mycotoxins in grain and its products]. Gig Sanit. 1989;(9):53-4.
[29]
Engler KH, Coker R, Evans IH. A novel colorimetric yeast bioassay for detecting trichothecene mycotoxins. J Microbiol Methods. 1999;35(3):207-18.
[30]
Engler KH, Coker RD, Evans IH. Uptake of aflatoxin B1 and T-2 toxin by two mycotoxin bioassay microorganisms: Kluyveromyces marxianus and Bacillus megaterium. Arch Microbiol. 2000;174(6):381-5.
[31]
Cahill LM, Kruger SC, McAlice BT, Ramsey CS, Prioli R, Kohn B. Quantification of deoxynivalenol in wheat using an immunoaffinity column and liquid chromatography. J Chromatogr A. 1999;859(1):23-8.
[32]
Razzazi-Fazeli E, B?hm J, Luf W. Determination of nivalenol and deoxynivalenol in wheat using liquid chromatography-mass spectrometry with negative ion atmospheric pressure chemical ionisation. J Chromatogr A. 1999;854(1-2):45-55.
[33]
Yagen B, Bialer M, Sintov A. Gas chromatographic assay with pharmacokinetic applications for monitoring T-2 and HT-2 toxins in plasma. J Chromatogr. 1985;343(1):67-75.
[34]
Tutelyan VA, Eller KS, Sobolev VS. Methodological guidelines for detection, identification and determination of the content of T-2 toxin and food and food raw materials. M., 1984; 9 p.
[35]
Schothorst R., Jekel A. Determination of trichothecenes in wheat by capillary gas chromatography with flame ionisation detection. Food Chemistry. 2001;73(1):111–7.
[36]
Chu FS, Grossman S, Wei RD, Mirocha CJ. Production of antibody against T-2 toxin. Appl Environ Microbiol. 1979;37(1):104-8.
[37]
Lee S, Chu FS. Radioimmunoassay of T-2 toxin in corn and wheat. J Assoc Off Anal Chem. 1981;64(1):156-61.
[38]
Gendloff EH, Pestka JJ, Swanson SP, Hart LP. Detection of T-2 toxin in Fusarium sporotrichioides-infected corn by enzyme-linked immunosorbent assay. Appl Environ Microbiol. 1984;47(5):1161-3.
[39]
Hunter KW Jr, Brimfield AA, Miller M, Finkelman FD, Chu SF. Preparation and characterization of monoclonal antibodies to the trichothecene mycotoxin T-2. Appl Environ Microbiol. 1985;49(1):168-72.
[40]
Fan TSL, Zhang GS, Chu FS. An indirect enzymelinked immunosorbent assay for T-2 toxin in biological fluids. J Food Protec. 1984; 47(12): 964-7.
[41]
Kononenko GP, Burkin AA, Soboleva NA, Zotova EV. Enzyme immunoassay method for the determination of T-2 toxin in contaminated grain. Prikl Biokhim Mikrobiol. 1999; 35(4):457-62.
[42]
Ramakrishna N, Lacey J, Candlish AA, Smith JE, Goodbrand IA. Monoclonal antibody-based enzyme linked immunosorbent assay of aflatoxin B1, T-2 toxin, and ochratoxin A in barley. J Assoc Off Anal Chem. 1990;73(1):71-6.
[43]
Ligler FS, Bredehorst R, Talebian A, Shriver LC, Hammer CF, Sheridan JP, Vogel CW, Gaber BP. A homogeneous immunoassay for the mycotoxin T-2 utilizing liposomes, monoclonal antibodies, and complement. Anal Biochem. 1987;163(2):369-75.
[44]
Mirocha CJ, Panthre SV, Pawlosky RJ, Hewetson DW. Mass spectra of selected trichothecenes. Modern Methods in the Analysis and Structure Elucidation of Mycotoxins. Ed. R. J. Cole. New York: Acad, press, 1986: 353-392.
[45]
Vesonder RF, Rohwedder WK. Gas chromatographic-mass spectrometric analysis of mycotoxins. Modern Methods in the Analysis and Structure Elucidation of Mycotoxins. Ed. R. J. Cole. New York: Acad, press, 1986: 335-352.
[46]
Omurtag GZ, Yazicio?lu D. Occurrence of T-2 toxin in processed cereals and pulses in Turkey determined by HPLC and TLC. Food Addit Contam. 2001;18(9):844-9.
[47]
Tanaka T, Yoneda A, Inoue S, Sugiura Y, Ueno Y. Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography-mass spectrometry. J Chromatogr A. 2000;882(1-2):23-8.
[48]
Kostiainen R, Matsuura K, Nojima K. Identification of trichothecenes by frit-fast atom bombardment liquid chromatography—high-resolution mass spectrometry. J Chromatogr A. 1991;538(2):323–30.
[49]
Nielsen KF, Thrane U. Fast methods for screening of trichothecenes in fungal cultures using gas chromatography-tandem mass spectrometry. J Chromatogr A. 2001;929(1-2):75-87.
[50]
Mullett W, Lai EP, Yeung JM. Immunoassay of fumonisins by a surface plasmon resonance biosensor. Anal Biochem. 1998;258(2):161-7.