Biopolym. Cell. 2002; 18(6):478-484.
Огляди
Глікоалкалоїди картоплі: розповсюдженість, фізико-хімічні
властивості, токсичність і методи визначення
- Інститут молекулярної біології і генетики НАН України
Вул. Академіка Заболотного, 150, Київ, Україна, 03680
Abstract
В огляді обговорюються деякі аспекти проблеми, пов'язаної з
токсичністю глікоалколоїдів (ГА) картоплі, зокрема, розповсюдженість у природі, класифікація, фізико-хімічні властивості і структурно активні компоненти ГА, токсичні ефекти
та фактори ризику, існуючі і нові методи для визначення
концентрацій Г А у харчових продуктах та біологічних рідинах.
Зроблено спробу відповісти на одне з найважливіших питань,
що виникає при узагальненні нагромаджених знань, – наскільки ГА картоплі безпечні для людини та тварин.
Повний текст: (PDF, російською)
References
[1]
Morgan MR, Coxon DT. Tolerances: glykoalkaloids in potatoes. Natural toxicants in food progr. and prospects. Ed. D. H. Watson-Weinheim: VCH, 1987: 221-30.
[2]
Phillips BJ, Hughes JA, Phillips JC, Walters DG, Anderson D, Tahourdin CS. A study of the toxic hazard that might be associated with the consumption of green potato tops. Food Chem Toxicol. 1996;34(5):439-48.
[3]
Slanina P. Solanine (glycoalkaloids) in potatoes: toxicological evaluation. Food Chem Toxicol. 1990;28(11):759-61.
[4]
Wolf MJ, Duggar BM. Estimation and physiological role of solanine in the potato. J Agric Res. 1946;73:1-32.
[5]
Jadhav SJ, Sharma RP, Salunkhe DK. Naturally occurring toxic alkaloids in foods. Crit Rev Toxicol. 1981;9(1):21-104.
[6]
Schwarze P. Methods for identification and determination of solanine in potato breeding material. Zuechter. 1962; 32: 155-160.
[7]
Allen EH, Kuc J. a-Solanine and a-chaconine as fungitoxic compounds in extracts of Irish potato tubers. Phytopathology. 1968;58: 776-781.
[8]
Sinden SL, Sanford LL, Osman SF. Glycoalkaloids and resistance to the Colorado potato beetle in Solanum chacoense Bitter. Am Potato J. 1980;57(7):331–43.
[9]
Tingey WM. Glycoalkaloids as pest resistance factors. Am Potato J. 1984;61(3):157–67.
[10]
Friedman M. Composition and safety evaluation of potato berries, potato and tomato seeds, potatoes, and potato alkaloids. Food Safety Assessment, ACS Symp. Ser. 1992; 484: 429-462.
[11]
Guseva AR, Paseshnichenko VA. [Quantitative determination of gluco-alkaloids in potatoes and their separation]. Biokhimiia. 1956;21(5):585-90.
[12]
NIEHS (National Institute of Environmental Health Sciences). Information profile for NIEHS nominations on chemicals to the national toxicology program for a-chaconine. New York, 1997. 3 p.
[13]
NIEHS (National Institute of Environmental Health Sciences). Information profile for NIEHS nominations on chemicals to the national toxicology program for a-solanine. New York, 1997. 3 p.
[14]
Solanine I Ed. S. Budavari. New York: Merck and Co., Inc., 1996.
[15]
Brain KR, Turner TD. Toxic fruits in frozen peas. J Assoc Public Anal. 1971;9: 100-1.
[16]
Zaletskaya BG, Golynskaya LA, Zaletskii VN. Changes in the contents of glycoalkaloids during the manufacture, and storage of dried potato puree. Konserv. Ovoshchesush. Proms. 1977; 1: 13-4.
[17]
Morris SC, Lee TH. The toxicity and teratogenicity of Solanaceae glycoalkaloids, particularly those of the potato (Solanum tuberosum). Food Technol Austral. 1984; 36(3): 118-24.
[18]
Rothe JC. Illness following the eating of potatoes containing solanine. Z Hyg. 1918; 88: 1-10.
[19]
Harris FW, Cockburn T. Alleged poisoning by potatoes. Am J Pharmacol. 1918; 90: 722-26.
[21]
Wilson GS. A small outbreak of solanine poisoning. Mon Bull Minist Health Public Health Lab Serv. 1959;18:207-10.
[22]
McMillan M, Thompson JC. An outbreak of suspected solanine poisoning in schoolboys: Examinations of criteria of solanine poisoning. Q J Med. 1979;48(190):227-43.
[23]
Anonymous. Solanine food poisoning associated with a school lunch program. Diseases weekly report, health and welfare (Canada). Alberta, 1984; 71: 10-8.
[24]
Hellen?s K-E, Nyman A, Slanina P, L??f L, Gabrielsson J. Determination of potato glycoalkaloids and their aglycone in blood serum by high-performance liquid chromatography. J Chromatogr B: 1992;573(1):69–78.
[25]
Nishie K, Gumbmann MR, Keyl AC. Pharmacology of solanine. Toxicol Appl Pharmacol. 1971;19(1):81-92.
[26]
Patil BC, Sharma RP, Salunkhe DK, Salunkhe K. Evaluation of solanine toxicity. Food Cosmet Toxicol. 1972;10(3):395-8.
[27]
Terbruggen A. Deadly solanine poisoning and a report on the meaning of brain swelling with decreased skull capacity. Beitr Pathol Anat Allg Pathol. 1936; 97: 391-5.
[28]
Willimott SG. An investigation of solanine poisoning. Analyst. 1933; 58(689): 431-8.
[29]
Bomer A, Mattis H. Solanine content of potatoes. Z. Unters. Nahr. Genussm. Gebrauchsgegenstande. 1924; 47: 97-127.
[30]
Whittaker M. Pseudocholinesterase variants: a study of forteen families selected via the fluoride resistant phenotype. Acta genet statist med. 1967; 17: 1-12.
[31]
Rayburn JR, Friedman M, Bantle JA. Synergistic interaction of glycoalkaloids alpha-chaconine and alpha-solanine on developmental toxicity in Xenopus embryos. Food Chem Toxicol. 1995;33(12):1013-9.
[32]
Aubert S, Daunay M, Pochard E. Saponins and steroidal alkaloids of eggplant (Solanum melongena). J Food Interest Analyt Meth Localization in Fruit Agronomie. 1989; 9: 641-51.
[33]
Nigg HN, Ramos LE, Graham EM, Sterling J, Brown S, Cornell JA. Inhibition of human plasma and serum butyrylcholinesterase (EC 3.1.1.8) by alpha-chaconine and alpha-solanine. Fundam Appl Toxicol. 1996;33(2):272-81.
[34]
Friedman M, Dao L. Distribution of glycoalkaloids in potato plants and commercial potato products. J Agric Food Chem. 1992;40(3):419–23.
[35]
Sharma R, Salunkhe D. Solanum glycoalkaloids. Toxicants of plant origin. Alkaloids. Ed. P. R. Cheeke. Boca Raton: CRS press, 1989. Vol. I: 179-236.
[36]
Clement E, Verbist JF. Determination of solanine in Solanum tuberosum L. tubers: comparative study of 9 colorimetric methods. Lebensmitt. Wiss.+Technol. 1989; 13: 202-6.
[37]
Chen S, Derrick PJ, Mellon FA, Price KR. Analysis of glycoalkaloids from potato shoots and tomatoes by four-sector tandem mass spectrometry with scanning-array detection: comparison of positive ion and negative ion methods. Anal Biochem. 1994;218(1):157-69.
[38]
Ferreira F, Moyna P, Soule S, V?zquez A. Rapid determination of solanum glycoalkaloids by thin-layer chromatographic scanning. J Chromatogr A. 1993;653(2):380–4.
[39]
Simonovska B, Vovk I. High-performance thin-layer chromatographic determination of potato glycoalkaloids. J Chromatogr A. 2000;903(1-2):219-25.
[40]
Herb SF, Fitzpatrick TJ, Osman SF. Separation of potato glycoalkaloids by gas chromatography. J Agric Food Chem. 1975;23(3):520-3.
[41]
Hellen?s KE, Branzell C. Liquid chromatographic determination of the glycoalkaloids alpha-solanine and alpha-chaconine in potato tubers: NMKL Interlaboratory Study. Nordic Committee on Food Analysis. J AOAC Int. 1997;80(3):549-54.
[42]
Sotelo A, Serrano B. High-Performance Liquid Chromatographic Determination of the Glycoalkaloids ?-Solanine and ?-Chaconine in 12 Commercial Varieties of Mexican Potato. J Agric Food Chem. 2000;48(6):2472–5.
[43]
Pat. USA. US 5614408. Monoclonal antibodies to potato, tomato, and eggplant glycoalkaloids and assays for the same. L. H. Stanker, C. K. Holtzapple. Publ. April 24, 1997.
[44]
Plhak LC, Sporns P. Enzyme immunoassay for potato glycoalkaloids. J Agric Food Chem. 1992;40(12):2533–40.
[45]
El'skay GV, Korpan YaI. Biosensor Technology: Realities and Prospects. Visn NAN Ukrainy. 2000; (3):36-40.
[46]
Korpan Y, Volotovsky V, Martelet C, Jaffrezic-Renault N, Nazarenko E, El’skaya A, Soldatkin A. A novel enzyme biosensor for steroidal glycoalkaloids detection based on pH-sensitive field effect transistors. Bioelectrochemistry. 2002;55(1-2):9–11.