Biopolym. Cell. 1999; 15(4):257-261.
Огляди
Висока селективність мутагеної дії синтетичних полінуклеотидів
1Александров Ю. М.
  1. Інститут фізіології рослин і генетики НАН України
    вул. Васильківська, 31/17, Київ, Україна, 03022

Abstract

Високомолекулярні розчини полірибо- та полідезоксирибонуклеотидів, шр введено у самців Drosophila melanogaster, збіль­шували у 6–17 разів частоту рецесивних летальнних мутацій у 2-й хромосомі. Комплементаційний аналіз індукованих ле­тальних мутацій виявив високу локус-специфічність для цих мутагенів. Обговорюються можливі механізми мутагенної дії синтетичних полінуклеотидів.

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