Biopolym. Cell. 1999; 15(3):195-199.
Огляди
Двоспіральні форми полі (А): можливе втягнення в біологічні процеси
1Зарудна М. І.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

В огляді стисло описано унікальні конформацій можливості поліаденілової кислоти- Обмірковано питання про можливість утворення подвійних оліго(А)-спіралей в PНK у біологічних системах. Висловлено припущення про те, що в основі стабілізаційної дії ELAV-подібних білків лежить їхня здатність стимулювати утворення внутрішніх подвійних оліго(А)-спіралей в полі(А) -хвостах специфічних мРНК

References

[1] Manley JL. Messenger RNA polyadenylylation: a universal modification. Proc Natl Acad Sci U S A. 1995;92(6):1800-1.
[2] Adler AJ, Grossman L, Fasman GD. Polyriboadenylic and polydeoxyriboadenylic acids. Optical rotatory studies of pH-dependent conformations and their relative stability. Biochemistry. 1969;8(9):3846-59.
[3] Finch JT, Klug A. Two double helical forms of polyriboadenylic acid and the pH-dependent transition between them. J Mol Biol. 1969;46(3):597-8.
[4] Janik B, Sommer RG, Bobst AM. Polarography of polynucleotides. II. Conformations of poly(adenylic acid) at acidic pH. Biochim Biophys Acta. 1972;281(2):152-68.
[5] Lerner DB, Kearns DR. Proton and phosphorus NMR investigation of the conformational states of acid polyadenylic double helix. Biopolymers 1981 20(4):803—16.
[6] Zarudnaya MI, Zheltovskii NV. Affinity electrophoresis investigation of the interaction between homopolyribonucleotides and the lysine ester dication. Mol. Biol (Mosk). 1992 26(1):110—117.
[7] Zarudnaia MI, ZHeltovskii NV. Electrophoretic study of conformational transitions in poly(A) at acid pHs. Mol Biol (Mosk). 1995;29(5):1040-7.
[8] Zarudnaya MI. Study of conformational transitions in poly (A) by the buffer capacity technique. Mol Biol (Mosk). 1998;32(3):508-14.
[9] Holcomb DN, Timasheff SN. Temperature dependence of the hydrogen ion equilibria in poly(riboadenylic acid). Biopolymers. 1968;6(4):513-29.
[10] Bobst AM, Rottman F, Cerutti PA. Effect of the methylation of the 2'-hydroxyl groups in polyadenylic acid on its structure in weakly acidic and neutral solutions and on its capability to form ordered complexes with polyuridylic acid. J Mol Biol. 1969;46(2):221-34.
[11] Thrierr C, Leng M. A study of methylated polyadenylic acid. Eur J Biochem. 1971;19(1):135-42
[12] Ikehara M, Hattori M, Fukui T. Synthesis and properties of poly(2-methyladenylic acid). Formation of a poly(A)-poly(U) complex with Hoogsteen-type hydrogen binding. Eur J Biochem. 1972;31(2):329-34.
[13] Samijlenko SP, Kolomiets IM, Kondratyuk IV, Stepanyugin AV. Model considerations on physico-chemical nature of protein-nucleic acid contacts through amino acid carboxylic groups: spectroscopic data. Biopolym. Cell. 1998; 14(1):47-53
[14] Kondratyuk IV. Investigation of physico-chemical nature of elementary processes of molecular recognition by NMR, vibrational spectroscopy and computer simulation Kyiv: Ph. D. Thesis, 1996. 19 p.
[15] Hartman KA, McDonald-Ordzie PE, Kaper JM, Prescott B, Thomas GJ Jr. Studies of virus structure by laser-Raman spectroscopy. Turnip yellow mosaic virus and capsids. Biochemistry. 1978;17(11):2118-23.
[16] Prescott B, Sitaraman K, Argos P, Thomas GJ Jr. Protein-RNA interactions in belladonna mottle virus investigated by laser Raman spectroscopy. Biochemistry. 1985;24(5):1226-31.
[17] Hellendoorn K, Michiels PJ, Buitenhuis R, Pleij CW. Protonatable hairpins are conserved in the 5'-untranslated region of tymovirus RNAs. Nucleic Acids Res. 1996;24(24):4910-7.
[18] Zarudna MI. The formation of poly (A) double-stranded helices and their possible role in biological processes. 2-nd Meeting UBS Kharkiv, 1998, p 11.
[19] Zarudna MI, Hovorun DM. Structural transitions in poliadeniloviy acid: possible molecular mechanisms of the functioning of mRNA poly (A) tails. Dopovidi Nats Akad Nauk Ukrainy. 1998;(12):155-60.
[20] Rich A, Diivies DR, Crick FHC, Watson JD. The molecular structure of polyadenylic acid. J Mol Biol. 1961;3:71-86.
[21] Birih KR. Conference "Molecular biology of RNA: translation, stability and localization of mRNA". Rus. J. Bioorg. Chem 1998 24, N 6:476—478.
[22] Sachs A, Wahle E. Poly(A) tail metabolism and function in eucaryotes. J Biol Chem. 1993;268(31):22955-8.
[23] Ma WJ, Chung S, Furneaux H. The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA. Nucleic Acids Res. 1997;25(18):3564-9.
[24] Fan XC, Steitz JA. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 1998;17(12):3448-60.
[25] Peng SS, Chen CY, Xu N, Shyu AB. RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J. 1998;17(12):3461-70.
[26] Abe R, Sakashita E, Yamamoto K, Sakamoto H. Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC. Nucleic Acids Res. 1996;24(24):4895-901.
[27] Sachs A. B., Davis R. W., Kornberg R. D. A single domain of yeast poly (A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol Cell Biol. 1987;7(9):3268-76.
[28] Nemeth A, Krause S, Blank D, Jenny A, Jen? P, Lustig A, Wahle E. Isolation of genomic and cDNA clones encoding bovine poly(A) binding protein II. Nucleic Acids Res. 1995;23(20):4034-41.
[29] Burd CG, Dreyfuss G. Conserved structures and diversity of functions of RNA-binding proteins. Science. 1994;265(5172):615-21.
[30] Zarudnaya MI. Co-operative formation of three double helical forms of poly (A): proton buffer capacity and electrophoresis data. Conf. on Physics of Biol, systems Kyiv, 1998:52.
[31] Brahms J, Michelson AM, Van Holde KE. Adenylate oligomers in single- and double-strand conformation. J Mol Biol. 1966;15(2):467-88.
[32] de Melo Neto OP, Standart N, Martins de Sa C. Autoregulation of poly(A)-binding protein synthesis in vitro. Nucleic Acids Res. 1995;23(12):2198-205.