Biopolym. Cell. 1998; 14(3):223-230.
http://dx.doi.org/10.7124/bc.0004D1
Геном та його регуляція
Регуляція генів інтерферонів І типу та інтерферон-індукованих генів. 1. Організація промоторних регуляторних послідовностей
1Карпов О. В.
  1. Інститут мікробіології і вірусології ім. Д. К. Заболотного НАН України
    вул. Академіка Заболотного, 154, Київ, Україна, 03680

Abstract

Наведено огляд відомостей щодо характеристики регуляторних послідовностей генів інтерферонів І типу (α- β-ІФН), а також ІФН-індукованих генів. Описано структурні характеристики доменів, які здійснюють позитивну і негативну регуляцію експресії даних, генів, а також функціональні особливості таких послідовностей у складі гетерологічних промоторів. З огляду на останні дані підкреслено значення конформації регуляторних послідовностей самих по собі і в складі транскрипційних комплексів для ефективності регуляції експресії даних генів.
Повний текст: (PDF, українською)

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