Biopolym. Cell. 1998; 14(1):12-18.
http://dx.doi.org/10.7124/bc.0004B2
Огляди
Радіорезистентність клітин пухлини
1Зінченко В. А.
  1. Український науково-дослідний інститут онкології та радіології МОЗ України
    ул. Ломоносова, 33/43, Киев, Украина, 03022

Abstract

В огляді проаналізовано дані світової літератури стосовно радіорезистентності (РР) бластом як природної, так і набутої внаслідок опромінення, що с найважливішою причиною недостатньої ефективності променевої терапії злоякісних новоутворень, а також виникнення рецидивів. Зроблено спробу прослідкувати взаємозв'язок деяких особливостей пухлин клітин та їх стійкості до опромінення у зв'язку з можливими механізмами PP. Розглянуто залежність РР від гетерогенності пухлинних клітин, структурно-функціональних змін їхніх ДНК, деякі біохімічні параметри, пов'язані з PP.
Повний текст: (PDF, українською)

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