Biopolym. Cell. 1997; 13(5):352-361.
http://dx.doi.org/10.7124/bc.000496
Огляди
Чому і як відмирають клітини тканин і органів?
1Стойка Р. С., 2Фільченков О. О., 3Стойка Б. Р.
  1. Відділення регуляторних систем клітини Інституту біохімії ім. О. В. Палладіна НАН України
    вул. Драгоманова 14/16, Львів, Україна, 79005
  2. Інститут експериментальної патології, онкології і радіобіології ім. Р. Є. Кавецького
    вул. Васильківська, 45, Київ, Україна, 03022
  3. Львівський національний медичний університет
    вул. Пекарська, 69, Львів, Україна, 79010

Abstract

В огляді охарактеризовано основні причини відмирання клітин тварин і людини, яке відбувається двома принципово відмінними шляхами, такими як апоптоз та некроз. Головну увагу звернено на механізми запрограмованої самоліквідації клітин шляхом апоптозу. Наведено дані про найваж­ливіші гени, що керують апоптозом. Зроблено висновок про перспективність вивчення молекуляр­них механізмів апоптозу з метою розробки нового покоління медичних препаратів для впливу на процеси клітинної загибелі, що має місце під час різних захворювань.
Повний текст: (PDF, українською)

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