Biopolym. Cell. 1994; 10(5):31-48.
http://dx.doi.org/10.7124/bc.0003BA
Бакуловірусна система експресії чужорідних генів – сучасне i майбутнє біотехнології одержання біологічно активних білків різного походження
1Кіхно І. М., 1Строковська Л. І.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

Узагальнено дані, що стосуються високоефективної системи експресії на основі рекомбіантних бакуловірусів у культурі клітин або в організмі комах. Проаналізовано особливості молекулярно-генетичної організації бакуловірусів, яі! дозволяють використовувати їx як суперпродуцентів білків piзнoгo походження. Розглянуто підходи, за допомогою яких можна досягти максимального виходу біологічно активного про­дукта в дашй системі експресії. Обгрунтовано переваги рекомбіантних бакуловіруciв як експресійних векторів та високоефективних біоінсектецидів.
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