Biopolym. Cell. 1992; 8(6):30-34.
Structure and Function of Biopolymers
Protein biosynthesis in cell-free systems from rabbit liver under experimental myocardial ischemia
1Mashanauskas T. K., 1Ivanov L. L., 1Rodovichius H. A., 1Lukoshevichius L. J., 1Prashkevichius A. K.
- Kaunas Medical Academy
Mizkevicha Str. 9, Kaunas, Lithuania, 44307
Abstract
The level of protein biosynthesis in cell-free systems from rabbit liver was studied both in norm and 12 h after experimental myocardial ischemia (EMI). The results demonstrate that the rise in the level of [14C]-leucine incorporation into translational product in cell-free system under EMI is related to the increase of aminoacyl-tRNA synthetase activity. Electrophoretical analysis of the translational products with subsequent fluorography has revealed redistribution in the spectrum of the proteins synthesized in cell-free system under EMI.
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