Biopolym. Cell. 1990; 6(6):72-79.
A software package for analysing amino acid sequences by personal microcomputer «ISKRA-226»
1Kostetsky P. V., 1Artemyev I. V., 1Pozhiltsova O. I., 1Ulyashin V. V.
  1. M. M. Shemyakin Institute of Bioorganic Chemistry, Academy of Sciences of the USSR
    Moscow, USSR

Abstract

Presented software package allows: 1) input and edition of amino acid sequences; 2) listing of aligned amino acid sequences of homologous protein; 3) pairwise comparison of homologous sequences; 4) calculation of phylogenetic trees of homologous protein sequences; 5) identification of variable and constant regions of amino acid sequences; 6) search for similarity between two amino acid sequences and list out comparison dot matrix; 7) prediction of B- and T-cell antigenic determinants; 8) trans forming Protein Identification Resource (PIR) from magnetic tape media to «Iskra-226» floppy disk media and vice versa; 9) identification of structure gene fragments using a set of peptides;. 10) translation of structure genes containing introns. Programs are written in BASIC for a personal computer «Iskra-226» (USSR). To accelerate some operations, computer code commands are used. Software package is realized in interactive mode and intended for specialists on peptide and protein chemistry.

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