Biopolym. Cell. 2005; 21(5):381-391.
http://dx.doi.org/10.7124/bc.000700
Reviews
Chaperone-like properties of the protein synthesis components
1Lukash T. O., 1Turkivska H. V.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680

Abstract

The review analyzes the results of research concerning chaperone- like properties of the ribosomes and translation factors. In addition to their role in the protein biosynthesis, pro- and eukaryotic ribosomes, elongation factors EF1A, eEFIA, EF2 and initiation factor 1F2 are able to promote the reactivation of several partly denatured enzymes and protect them against denaturation. We conclude, that chaperone-like activity of the ribosomes and translational factors might be important for maintaining the enzymes activities in the cytoplasm.
Keywords: molecular chaperone, folding, protein synthesis system, ribosomes, protein translation factors
Full text: (PDF, in Ukrainian)

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