Biopolym. Cell. 2005; 21(1):12-27.
Reviews
Protein S-100: structural and functional properties and role in
nervous tissue
1Nikandrov V. N., 1Chaplinskaya E. V.
- Institute of Physiology , NAS of Belarus
28, Academicheskaya Str., Minsk, Belarus, 220072
Abstract
The literature data are analyzed concerning the classification,
techniques of isolation, physical and chemical properties, localization in neuronal structures, dynamics in ontogenesis, mechanisms
of action and functional role in the nervous system, neurotrophic properties, and involvement of Ca2+ -binding proteins S-100 in the
pathogenesis of some diseases. The contribution of S-100 to the cellular and general intersystem mechanisms of life maintenance and adaptive activity in human and animal organisms is discussed
Keywords: S-100, nervous system, structure, functions, Ca2+
Full text: (PDF, in Russian)
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