Biopolym. Cell. 1996; 12(5):66-71.
PCR amplification, cloning and sequencing of cDNA fragment encoding a nucleotide binding domain of mammalian tyrosyl-tRNA synthetase
- Institute of Molecular Biology and Genetics, NAS of Ukraine
150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
Abstract
cDNA fragment encoding the N-terminal nucleotide binding domain (Rossmann fold) of mammalian tyrosyl-tRNA synthetase has been PCR-amplified, cloned and sequenced. The unique variant of conservative HIGH-like motif, HVA Y, where glycine residue was substituted by alanine, has been observed for the first time.
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