Biopolym. Cell. 1985; 1(3):115-120.
http://dx.doi.org/10.7124/bc.00001C
Structure and Function of Biopolymers
Histone conformers are the foundation of structural chromatin rearrangements
1Khrapunov S. N.
  1. Taras Shevchenko State University of Kiev
    Kiev, USSR

Abstract

Histone oligomers may be in several structural states. Local metabolically stable states of the native conformers insignificantly differ (are degenerated) in an energetic way and are separated by low barriers which may be overcome either under changed conditions (ionic strength, pH, polarity) or during the interaction of histone oligomers with cellular effectors. Structural histone conformer rearrangements occuring at the level of changes in the tertiary and quaternary structures may determine parallel with other factors struc¬tural chromatin rearrangements underlying expression and repression of the eucaryote genes.
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