Biopolym. Cell. 1992; 8(4):3-19.
Огляди
Білковий синтез та аутоімунітет
1Сидорик Л. Л.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

В огляді наведено літературні дані про особливості аутоантитілогенезу до деяких компонентів апарату трансляції. Розглянуто приклади виявлення аутоантитіл до аміноацилтРНК синтетаз, рибосом та рибосомних білків за Певних аутоімунних патологій частково охарактеризовано їх властивості порівняно з структурно-функціональними особливостями аутоантитіл до інших типів клітинних RNP – як цитоплазматичних, так і ядерних. Подано основні гіпотези походження аутоантитіл та їх функціонального значення в нормі і за імунопатологій.

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