Biopolym. Cell. 1989; 5(6):5-20.
Огляди
Механізми регуляції активності генів у кластері rplKAJL-rpoBC Escherichia coli
1Патон Є. Б.
- Інститут молекулярної біології і генетики АН УСРС
Київ, СРСР
Abstract
Описано механізми регуляції експресії генів у кластері rplKAJL-rpoBC E. coli, що реалізуються на рівні транскрипції і трансляції. Розглянуто, зокрема, функціональна роль структури мРНК, структура регуляторних рибосомних білків, сполучність трансляції поліцистронних мРНК, які кодують ці білки, транскрипційний контроль у «rif»-області та аутогенна регуляція синтезу β- і β'-субодиниць РНК-полімерази, а також особливості конструювання рекомбінантних ДНК, пов’язані з експресією цих генів.
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