Вітамин D – нова роль при вагітності

Арора Чандер, П.; Хобель, К. Дж.

doi:10.7124/bc.00014B

Biopolym. Cell. 2010; 26(2):97-104.

http://dx.doi.org/10.7124/bc.00014B

Огляди

Вітамин D – нова роль при вагітності

1, 2Арора Чандер П., 1, 2Хобель К. Дж.

Медичний центр Cedars-Sinai
Burns-Allen Дослідницький інститут;
8635, вул. Вест 3, 160 W, Лос-Анджелес, Каліфорнія, США, 90048
Медична школа Девіда Гріфіна
Каліфорнійського університету
10833 пр. Ле Конте, Лос-Анжелес, США, 90096

Abstract

Вітамін D регулює розвиток і функцію плаценти. Він є потужним регулятором імунної системи, що стимулює антибактерійну відповідь та пригнічує запалення. Його дефіцит при- зводить до зростання ризику серйозних хронічних і запальних захворювань. Протягом вагітності дефіцит вітаміну D підвищує сприйнятливість жінок до інфекцій і запалення, спричиняє передчасні пологи та прееклампсію. Вагітні жінки з темнішою пігментацією шкіри, які живуть у місцях з низьким рівнем сонячного світла, частіше страждають від дефіциту вітаміну D. При вагітності можлива активація первинного неінфекційного запального процесу внаслідок нестачі вітаміну D. Виявлення дефіциту вітаміну D і запальних маркерів на різних стадіях вагітності може полегшити розпізнавання ризику будь-яких ускладнень.

Keywords: вітамін D, вагітність, імунна відповідь

Повний текст: (PDF, англійською)

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