Biopolym. Cell. 2000; 16(4):301-311.
http://dx.doi.org/10.7124/bc.000576
Геном та його регуляція
Екстрахромосомні ДНК у клітинах еукаріот
1Крисан К. В.
  1. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

Відомо дві основні форми існування трансгенів – інтегрована в геном реципієнта та екстрахромосомна. Хоча інтегровані трансгени зустрічаються значно частіше, ніж таки які здатні до сталого позахромосомного існування, останні є набагато цікавішими і перспективнішими для біотехнології та біомедицини. Однак механізми, що визначають форму існування екстрахромосомних ДНК, наразі досліджені ще недостатньо. В даному огляді проаналізовано ці механізми та розглянуто екстрахромосомні ДНК різного походження
Повний текст: (PDF, українською)

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