Biopolym. Cell. 1990; 6(1):73-82.
Some ultrastructural aspects of direct injection of liposomes with inclosed plasmid DNA into mice liver
- Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
After direct injection of liposomes with inclosed bacterial b-galactosidase gene into mice liver the main ultrastructural changes have been observed in mitochondria and Goldgi region. Liposomes themselves were investigated by transmission electron microscopy of ultrathin sections. An attempt was made to elucidate their distributon in mice liver after direct injection.
 Spanjer HH, van Galen M, Roerdink FH, Regts J, Scherphof GL. Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition. Biochim Biophys Acta. 1986;863(2):224-30.
 Kostetsky IE, Shpilevaya SP, Likhacheva LI, Zharova LC, Irodov DM, Kirillova VS, Kordium VA. Expression of Escherichia coli?-Galactosidase in murine hepatocytes. Biopolym. Cell. 1989; 5(2):51-8.
 Margolis LB, Breygelson LD. Liposomes and their interaction with cells. Moscow, Nauka, 1986; 240 p.
 Margolis LB. Mechanisms of interaction of liposomes with cells: prospects and limitations of liposomes in the science and practice. Biologicheskiye membrany. 1987; 4(5):453-67.
 Belitser NV, Chernyshov VI, Anishchuk MG, Kozlova TR, Stefanov AV. Interaction of negatively charged lecithin liposomes with human erythrocytes: a transmission electron microscopy study of ultrathin sections. Dokl Akad Nauk SSSR. 1984;277(1):210-3.
 Belitser NV, Anischuk MG, Chernishov VI, Kozlova TR. Interaction of positively charged liposomes with erythrocyte membrane. An ultrastructural study. Cell Biol Int Rep. 1986;10(5):331-8.
 Chernyshev VI, Kozlov TR, Sokolov YuV. Adsorption and fusion of positively charged liposomes with human erythrocyte membrane. Electron microscopy of ultrathin sections. Biologicheskiye membrany. 1987; 4 (1) :90-5.
 Kordium VA. Objectives and problems of gene therapy. Biopolym. Cell. 1989; 5(2):5-16.
 Takahashi G. Tannin-ferrocyanide OsO4 method for transmission and scanning electron microscopy. Proc. XI Int. Congr. on electron microscopy. Kyoto, 1986. 345 p.
 Loud AV. A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells. J Cell Biol. 1968;37(1):27-46.
 Cudd A, Labbe H, Gervais M, Nicolau C. Liposomes injected intravenously into mice associate with liver mitochondria. Biochim Biophys Acta. 1984;774(2):169-80.
 Cudd A, Nicolau C. Intracellular fate of liposome-encapsulated DNA in mouse liver. Analysis using electron microscope autoradiography and subcellular fractionation. Biochim Biophys Acta. 1985;845(3):477-91.
 Cudd A, Nicolau C. Interaction of intravenously injected liposomes with mouse liver mitochondria. A fluorescence and electron microscopy study. Biochim Biophys Acta. 1986;860(2):201-14.
 Geyer G. Electronic histochemistry. Moscow, Mir, 1974; 488 p.