Biopolym. Cell. 1994; 10(1):3-30.
Genome variability and accumulation of indoline alkaloids in Rauwolfia serpentina Benth. Cell culture
1Kunakh V. A.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


Literature data and results of our studies performed in 1979–1993 were summarized. The major outcome of our investigations was the establishment of novel cell strains-producents and the development of conditions for their maintaining that increased the accumulation of indoline alkaloid, ajmaline, up to 6–8 % and occasionally up to 20 %. This is 100-fold higher that of inherent to 5–7 old plants growing in tropics.


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