Influence of ion interactions on the conformation of ribozyme specific to HIV-1 tat-RNA in solution

Authors

  • O. Yu. Markelova Institute of Molecular Biology and Genetics, NAS of Ukraine 150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680 Author
  • L. N. Buryanovsky Institute of Molecular Biology and Genetics, NAS of Ukraine 150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680 Author
  • O. E. Kitam Institute of Molecular Biology and Genetics, NAS of Ukraine 150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680 Author
  • K. F. Krasnova Institute of Molecular Biology and Genetics, NAS of Ukraine 150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680 Author
  • A. D. Shved Institute of Molecular Biology and Genetics, NAS of Ukraine 150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680 Author

DOI:

https://doi.org/10.7124/bc.000627

Abstract

Using the method of partial nudease hydrolysis it was shown that the medium ion composition essentially influenced tertiary interactions in the ribozyme molecule and changed its spatial structure.

References

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Published

2002-09-20

Issue

Section

Short Communications