Biopolym. Cell. 1993; 9(6):63-66.
Cell Biology
The purification of the main tissue-specific antigens from the normal and effected by dilatative cardiomyopathia human heart
1Bobik V. I., 1Veberov A. V., 2Ryabenko D. V., 2Dubrovskaya G. V., 1Rodnin N. V., 1Sidorik L. L.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
  2. M. D. Strazhesko Institute of Cardiology, MAS of Ukraine
    5, Narodnogo Opolchennya Str., Kyiv, Ukraine, 03151


The methods for the purification of the main tissue-specific antigens-(actin, myosin and tropomyosin) from the normal and affected by dilatative cardiomyopathia human heart are described. Some their physico-chemical properties were investigated. The dicrease of the contractive proteins content in the DCMP myocard in comparisons with the normal was shown.


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