Biopolym. Cell. 1993; 9(3):52-54.
Short Communications
DNA rearrangements in regenerating liver revealed by genomic fingerprinting
- Institute of Molecular Biology and Genetics, NAS of Ukraine
150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680
Abstract
By means of genomic fingerprinting in the cells of regenerating 23 h rat liver were revealed alterations of DNA fingerprint (in the region 1,5–9 kb) comparatively to cells of the same liver at rest. It may be explained by selective under-replication of chromosomes of deviding hepatocytes.
Full text: (PDF, in Russian)
References
[1]
Jeffreys AJ, Wilson V, Thein SL. Hypervariable 'minisatellite' regions in human DNA. Nature. 1985 Mar 7-13;314(6006):67-73.
[2]
Ivanov PL. DNA fingerprinting: hypervariable loci and genetic marking. Mol Biol (Mosk). 1989;23(2):341-7.
[3]
Genome Analysis: A Practical Approach. Ed. Davies KE. Oxford University Press. 1988. 208 p.
[4]
Higgins GM, Anderson RM. Experimental pathology of the liver. Arch Pathol. 1931; 12(2):186-202.
[5]
DNA Cloning: a practical approach. Ed. Glover DM. Vol. III. Oxford University Press. 1987; 272 p
[6]
Olszewska E, Jones K. Vacuum blotting enhances nucleic acid transfer. Trends Genet. 1988;4(4):92-4.
[7]
Rogayev EI, Lenskiy AB. Probe DNA containing the gene elements of surface glycoprotein of HIV-1. effective molecular marker for human fingerprinting. Bull Exp Biol Med. 1990. 12: 646-647.
[8]
Hodgson CP, Fisk RZ. Hybridization probe size control: optimized 'oligolabelling'. Nucleic Acids Res. 1987;15(15):6295.
[9]
Grisham JW. A morphologic study of deoxyribonucleic acid synthesis and cell proliferation in regenerating rat liver; autoradiography with thymidine-H3. Cancer Res. 1962;22:842-9.