Biopolym. Cell. 1993; 9(3):49-52.
Short Communications
Chronic influence effect of cooperative low-dosed irradiation on reproductive function of CC57W males and females mice
1Stolina M. R.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


The data have been obtained concerning the mutagienic effect of low-dosed enviromental and incorporated irradiation on germ cells of mice males and females. The high frequency of preimplantation embryo death has been shown for mice progeny, premeiotic germ cells at the stages of their multiplication and growth having been influenced by low-dosed irradiation. The critical developmental stages a prenathal one for females and the first, postnathal days for males, because of the formation of most stem spermatagonia in testis taking start at this period.


[1] Shevchenko VA, Pomerantseva M. D. Genetic effects of ionizing radiation. Moscow: Nauka, 1985. 280 p.
[2] Pomerantseva MD, Balonov MI, Rama?a LK, Chetchueva ME, Zhesko TV. Comparative study of the genetic effect of various tritium compounds in male mice. Genetika. 1989;25(2):277-82.
[3] Pomerantseva MD, Ramaya LK, Shevchenko VA, Vilkina GA, Lyaginskaya AM. Evaluation of the genetic effects of 238Pu incorporated into mice. Mutat Res. 1989;226(2):93-8.
[4] Bocharova LP, Vasilenko OV, Strel'nikova NK. Dependence of the reproductive function of mice from local irradiation dose, conducted at different times before and after conception. Radiation Hygiene. L., 1989: 75-81.
[5] Pomerantseva MD, Rama?ia LK. The yield of genetic disorders in mice exposed to the action of fractionated ionizing radiation in embryogenesis. Radiobiologiia. 1990;30(3):339-43.
[6] Yamada T, Ohta K, Fujii Y, Nakada S, Ohyama H, Darussalam M. Estimation of the Absorbed Radiation Dose of Mouse Foetus Taken from Tritium Water-Drinking Pregnant Mouse. J Radiat Res. 1991; 32(1):91.
[7] Prakash Hande M, Ume Devi P, Jagetia GC. Effect of "in utero" exposure to low doses of low energy X-rays on the postnatal development of mouse. J Radiat Res. 1990;31(4):354-60.
[8] Ricoul M, Dutrillaux B. Chromosome hyper-radiosensitivity in mice at the end of pregnancy. C R Acad Sci III. 1991;312(13):635-9.
[9] Hoover-Plow J, Elliott P, Moynier B. Reproductive performance in C57BL and I strain mice. Lab Anim Sci. 1988;38(5):595-602.
[10] Spiegelman M, Bennett D. A light- and electron-microscopic study of primordial germ cells in the early mouse embryo. J Embryol Exp Morphol. 1973;30(1):97-118.
[11] Agarkov VA, Dunayev PV, Panteleyev SM at al. Response of tissues of different genetic nature of the effects of ionizing radiation. Anthropogenic influence on morphogenesis and structural transformation of bodies: Materials Vseros. conf. Vseros. scientific. Society of Anatomists, histology, embryology. Astrakhan, 1991: 5.
[12] Pomerantseva MD, Ramaiya LK. The mutagenic effect of different types of irradiation on the germ cells of male mice. I. The comparative genetic radiosensitivity spermatogonia and of the other stages of the spermatogenesis. Genetika. 1969; 5(5): 103-12.