Biopolym. Cell. 1991; 7(5):103-107.
http://dx.doi.org/10.7124/bc.0002FA
Genome and Its Regulation
Determination of replicative activity of recombinant plasmids carrying SV40 eukaryotic regulatory region in mammalian cell cultures
1Landau S. M., 1Tichonov A. V., 1Varzanova I. S., 1Zharova L. G.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR

Abstract

The recombinant plasmids replication in mammalian cell cultures has been employed as a method for estimating the functional activity of SV40 eukaryotic regulatory region. It was shown that recombinant plasmids examined replicate in mammalian cell cultures and therefore possess functional active SV40 regulatory region. This method can be used for the purposes of gene therapy.
Full text: (PDF, in Russian)

References

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