Biopolym. Cell. 1990; 6(5):59-64.
http://dx.doi.org/10.7124/bc.00028E
Structure and Function of Biopolymers
Molecular organization of human serum albumin structure
1Ostolovsky E. M., 1Botsyansky A. D., 1Borisenko S. N., 1Tolkachova N. V.
  1. M. V. Frunze Simferopol State University,
    Simferopol, USSR

Abstract

Physicochemical methods (IR- and NMR-spectroscopy, circular dichroism, etc.) that human serum albumin molecule is a compact globule with 50 % spiral structure and with exposition of a half of tyrozil on its surface. At the same time considerable percent of polypeptide chain with disordely packed form and with small contribution of β-structure part is observed in the molecule space structure. Theoretical calculations of α-spiral parts localization in serum albumin molecule indicate that approximately equal number of amino acids residues is found in every of three domains.
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