Biopolym. Cell. 1990; 6(5):5-23.
http://dx.doi.org/10.7124/bc.000288
Reviews
Peculiarties of expression regulation of the rplKAJL gene cluster
1Paton E. B.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR

Abstract

The review is focused on the evolutionary point of structure and functional organization of the rplKAJL gene cluster, characteristics of the L1 and L10 regulatory ribosomal proteins and structural features of the L10-L7/L12 mRNA leader sequence, which contains a L10 binding site. The principles and specific features of the translational control of rplKAJL genes expression are considered and the regulatory mechanism, providing for the excess synthesis of L7/L12 protein in vivo is proposed. Peculiarities of recombinant molecules, caused by elevation of the cloned rplKAJL gene dosage in the cell, are discussed as well.
Full text: (PDF, in Russian)

References

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