Biopolym. Cell. 1990; 6(3):55-59.
http://dx.doi.org/10.7124/bc.00026C
Structure and Function of Biopolymers
Studies in pH-dependent structural and functional properties of lactate dehydrogenase in the presence of Zinc ions
1Kiladze A. A., 1Birkaya V. G., 1Lomidze E. M., 1Monaselidze J. R.
  1. Institute of Physics, Academy of Sciences of the Georgian SSR
    Tbilisi, USSR

Abstract

The effect of zinc, cobalt and nickel ions on the LDH structure and function was studied. Calorimetric data have revealed essentially different melting character of LDH and LDH bound with zinc, cobalt, and nickel ions. It is noteworthy that one zinc ion binding is specific for LDH M4. It is shown that zinc ion binding causes the changes in the LDH kinetic properties, no changes in LDH secondary structure occurring.
Full text: (PDF, in Russian)

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