Biopolym. Cell. 1990; 6(2):60-64.
Analysis of DNA polymorphism in the regions closely linked with cystic fibrosis gene in Kiev population
1Livshitz L. A., 1Gryshko V. I., 1Kravchenko S. A., 2Ivashchenko T. E., 2Baranov V. S., 1Buzhievskaya T. I.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR
  2. Institute of Obstetrics and Gynecology, Academy of Medical Sciences of the USSR
    Leningrad, USSR

Abstract

The allelic polymorphism of human DNA loci linked with cystic fibrosis gene (D7S23) was studied using polymerase chain reaction in the population of healthy donors in Kiev. The marked linkage disequilibrium between cystic fibrosis mutation and particular RELP alleles in D7S23) loci (KM-19-cndonuclease Pst I and CS.7-endonuclease Hin 61 systems) was found in the families with the affected children.

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