Biopolym. Cell. 1989; 5(6):68-72.
http://dx.doi.org/10.7124/bc.0000F9
Structure and Function of Biopolymers
Sizes of low-density lipoproteins in patients with ischemic heart disease and normolipidemia
1Vavrin R. Z., 2Kuznetzov A. S., 2Parfenova N. S., 1Noskin V. A., 2Olennikova L. V., 2Krivoruchenko I. V., 1Sungurov A. Yu., 2Kogan E. I., 2Magracheva E. Ya., 2Pivovarova Yu. I.
  1. B. P. Konstantinov Institute of Nuclear Physics, Academy of Sciences of the USSR
    Gatchina, Leningrad distr., USSR
  2. Institute of Experimental Medicine, Academy of Medical Sciences of the USSR
    Leningrad, USSR

Abstract

The properties of size-usual low-density lipoproteins (LDL) (R = 9.8±0.1nm), LDL of small size in healthy persons (R = 7.6±Q.l nm) and the size-small (R=7.7+0.1 nm)1 lipoproteins of the same class in patients with ischemic heart disease (IHD) are compared. It is shown that in healthy person LDL of small size were more inclined to aggregation than the LDL of usual size. As to the size-small lipoproteins in IHD, they are more instable than those in healthy persons. It is suggested, that LDL instability may be a risk factor of ishemic heart disease.
Full text: (PDF, in Russian)

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