Biopolym. Cell. 1989; 5(3):83-88.
http://dx.doi.org/10.7124/bc.0000C7
Structure and Function of Biopolymers
Fibronectin conformation with different ionic strength of the solution as determined by circular dichroism methods and thermal-perturbation differential spectroscopy
1Sykulev Yu. K., 1Tetin S. Yu., 1Atamas S. P., 1Matulskaya L. I., 1Panasyuk A. F., 2Troitsky G. V.
  1. Institute of Rheumatology, Academy of Medical Sciences of the USSR
    Moscow, USSR
  2. Crimean Medical Institute,
    Simferopol, USSR

Abstract

Conformation of plasma fibronectin was determined by circular dichroism and thermal perturbation differential spectroscopy with different ionic strength of the solution. It was found that conformational transition in fibronectin molecule, induced by an increase of the ionic solution strength was followed by no changes in secondary and tertiary structure of protein but was a result of changes in relative arrangement and domain-domain interaction in space.
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