Biopolym. Cell. 1989; 5(1):5-15.
Reviews
The nonelectrode biosensors as a new trend in the biochemical diagnostics
1Starodub N. F.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR

Abstract

The development of one of the most important trends of nontraditional biotechnology — construction of a new generation of diagnostical systems on the basis of nonelectrode sensorial equipments is analyzed. Characteristics of principally different biosensors (on the thermistors, piezoelectric crystals, semiconductive structures, etc.) including enzymes and antibodies as biologically active material are discussed. Information about the construction, usage and development of biosensors on the semiconductive structures is underlain because of their high sensitivity, availability, for individual noncentralized screening in regime of real time using multi- and implanted detector and some other preferences (technologicity, simplicity, miniaturity, reliability, cheapness).

References

[1] Starodub NF, El'skaia AV. Immunochemical aspects of the screening of gene expression. Tsitol Genet. 1988;22(5):64-72.
[2] Starodub NF, Artiukh VP, Nazarenko VI, Kolomiets LI. Protein immunoblot and immunodot in biochemical studies. Ukr Biokhim Zh. 1987;59(3):108-20.
[3] Smith OH. Biological transducers and coding. Biophys Sci. A study program. Ed. O. Wiley. New York, 1959: 110-115.
[4] Albery WJ, Haggett B, Snook D. You know it makes sensors. New Scientist. 1986; 109(1495):38-41.
[5] Scott A. Biosensors: a tool for the food and beverage industries? Lab Pract. 1985; 34(6):39-43.
[6] Place JF, Sutherland RM, Dahne C. Opto-electronic immunosensors: a review of optical immunoassay at continuous surfaces. Biosensors. 1985;1(4):321-53.
[7] Davis G. Advances in biomedical sensor technology: a review of the 1985 patent literature. Biosensors. 1986;2(2):101-24.
[8] Yalow RS, Berson SA. Immunoassay of endogenous plasma insulin in man. J Clin Invest. 1960;39:1157-75.
[9] Yaropolov AI, Berezin IV. The applications and prospects for further applications of biocatalysts in electrochemical systems. Russ Chem Rev. 1985; 54 (9):852-62.
[10] Frew JE, Hill AO. Electrochemical biosensors. Anal Chem. 1987;59(15):933A–944A.
[11] Strikha VI, Shul'ga OA. Biosensors based on semiconductor structures. Visnyk Akad Nauk UkrSSR. 1988;(2):21-33.
[12] Winquist F. Biosensors based on thermistors and semiconductor structures. Dissertation N 158 -Linkoping : Linkoping studies in science and technology, 1987. 100 p.
[13] Mela M., Huotari M., Ryymin P., Turunen J. Biosensors. Acta Univ Oul. 1986; 179:127-138.
[14] Frew JE, Hill HA. Electron-transfer biosensors. Philos Trans R Soc Lond B Biol Sci. 1987;316(1176):95-106.
[15] Aizawa M. Molecular recognition and chemical amplification of biosensors. Chem. sensors: proc. int. meet. Fukuoka etc, 1983:683-692.
[16] Owen VM. Non-electrode biosensors in clinical biochemistry. Ann Clin Biochem. 1985;22 (Pt 6):559-64.
[17] Shons A, Dorman F, Najarian J. An immunospecific microbalance. J Biomed Mater Res. 1972;6(6):565-70.
[18] Muramatsu H, Dicks JM, Tamiya E, Karube I. Piezoelectric crystal biosensor modified with protein A for determination of immunoglobulins. Anal Chem. 1987;59(23):2760-3.
[19] Roederer JE, Bastiaans GJ. Microgravimetric immunoassay with piezoelectric crystals. Anal Chem. 1983;55(14):2333–6.
[20] Calabrese GS, Wohltjen H, Roy MK. Surface acoustic wave devices as chemical sensors in liquids. Evidence disputing the importance of Rayleigh wave propagation. Anal Chem. 1987;59(6):833–7.
[21] Mosbach K, Danielsson B. Thermal bioanalyzers in flow streams. Enzyme thermistor devices. Anal Chem. 1981;53(1):83–94.
[22] Mosbach K, Matxdenius CF, Danielsson B. New biosensor devices. Biotech. 83: Proc. Int. conf. commer. appl. impl. biotech. inst. New York, 1983:665-78.
[23] Mattiasson B, Borrebaeck C, Sanfridson B, Mosbach K. Thermometric enzyme linked immunosorbent assay: TELISA. Biochim Biophys Acta. 1977;483(2):221-7.
[24] Freeman TM, Seitz WR. Chemiluminescence fiber optic probe for hydrogen peroxide based on the luminol reaction. Anal Chem. 1978;50(9):1242–6.
[25] Schultz JS, Mansouri S, Goldstein IJ. Affinity sensor: a new technique for developing implantable sensors for glucose and other metabolites. Diabetes Care. 1982;5(3):245-53.
[26] Goldfinch MJ, Lowe CR. Solid-phase optoelectronic sensors for biochemical analysis. Anal Biochem. 1984;138(2):430-6.
[27] Jordan DM, Walt DR, Milanovich FP. Physiological pH fiber-optic chemical sensor based on energy transfer. Anal Chem. 1987;59(3):437–9.
[28] Sutherland R, Dahne C, Place J. Preliminary results obtained with a No-Label, Homogeneous, Optical Immunoassay for Human Immunoglobulin G. Anal Lett. 1984; 17(1):43-53.
[29] Schultz JS. Fiberoptic biosensors in artificial organs. ASAIO Trans. 1986;32(2):705-10.
[30] Peterson J. I. Fiberoptic chemical sensors. A view from the past to the future. Proc. symp. biosens. Los Angeles etc: IEEE press, 1984:35-39.
[31] Krull UJ, Bloore C, Gumbs G. Communication. Supported chemoreceptive lipid membrane transduction by fluorescence modulation: the basis of an intrinsic fibre-optic biosensor. Analyst. 1986;111(2):259-61
[32] Martin MJ, Wickramasinghe YA, Newson TP, Crowe JA. Fibre-optics and optical sensors in medicine. Med Biol Eng Comput. 1987;25(6):597-604. Review. PubMed
[33] Cheung P. W. Semiconductor-based chemical sensors and their applications in medicine and biology. Proc . symp. biosens. Los Angeles etc: IEEE press, 1984:13-17.
[34] Winquist F, Lundström I, Danielsson B. Determination of creatinine by an ammonia-sensitive semiconductor structure and immobilized enzymes. Anal Chem. 1986;58(1):145-8.
[35] Caras S, Janata J. Field effect transistor sensitive to penicillin. Anal Chem. 1980;52(12):1935–7.
[36] Danielsson B., Winquist F., Mosbach K. Enzyme transistors. Biotech . 83 Proc. Int. conf. commer. appl. impl. biotech. inst. New York, 1983:679-688.
[37] Matsuo TEsashi M., Shibatani K. Catheter-tip pC02 and p02 sensors. Proc. symp. biosens. Los Angeles etc: IEEE press, 1984:33-34.
[38] Proceedings of International conference on solid-state sensors and actuators (Transducers, June 11-14, 1985). Philadelphia: IEEE press, 1985. 281 p.
[39] Sibbald A, Covington AK, Carter RF. Simultaneous on-line measurement of blood K+, Ca2+, Na+, and pH with a four-function ChemFET integrated-circuit sensor. Clin Chem. 1984;30(1):135-7.
[40] Sibbald A. Chemical biosensors and on-line patient monitoring. Med Instrum. 1985;19(4):164-7.
[41] Riedel K, Renneberg R, Liebs P, Kaiser G. Microbial sensors. Stud biophys. 1987; 119(1-3):163-6.
[42] Sibbald A. Recent advances in field-effect chemical microsensors. J Mol Electronics. 1986; 2(1):51-83.
[43] Aizawa M, Morioka A, Suzuki S. Enzyme immunosensor: II. Electrochemical determination of IgG with an antibodybound membrane. J Membrane Sci. 1978; 4(2):221-30.
[44] Janata J, Huber RJ. Solid state chemical sensors. New York: Acad, press, 1985. 211 p.
[45] Clark L. C., Noyes L. K. Theoretical and practical bases for implantable glucose sensors with special reference to the peritoneum. Proc. symp. biosens. Los Angeles etc: IEEE press, 1984:69-74.
[46] Lundstrom I, Spetz A, Winquist F, Albery WJ, Thomas JDR. Semiconductor Biosensors [and Discussion]. Phil Trans Roy Soc London B. 1987;316(1176):47–60.
[47] Kobos RK. Enzyme-based electrochemical biosensors. TrAC Trends in Anal Chem. 1987;6(1):6–9.
[48] Castner JF, Wingard LB Jr. Mass transport and reaction kinetic parameters determined electrochemically for immobilized glucose oxidase. Biochemistry. 1984;23(10):2203-10.
[49] Eddowes MJ. Response of an enzyme-modified pH-sensitive ion selective device; consideration of the influence of the buffering capacity of the analyte solution. Sensors and Actuators. 1985;7(2):97–115.
[50] Karube I, Matsuoka H, Suzuki S, Watanabe E, Toyama K. Determination of fish freshness with an enzyme sensor system. J Agric Food Chem. 1984;32(2):314–9.
[51] Owen VM. Biosensors. Sensor Review. 1985;5(1):20–4.
[52] Karube I.t Suzuki S. Immobilized enzymes for clinical analysis. Enzymes and immobilized cells in biotechnology. Eds A. I. Laskin, T. Benjamin. California: Cumming publ. co. inc., 1985. 209-226.
[53] Ko WH. Solid-state physical transducers for biomedical research. IEEE Trans Biomed Eng. 1986;33(2):153-62.