Biopolym. Cell. 2024; 40(3):234-234.
http://dx.doi.org/10.7124/bc.000AD5
Chronicle and Information
Adaptor protein CIN85 promotes collagen adhesion and invasion of osteosarcoma cells
1, 2Horak I. R., 2Drobot L. B., 1Knopfova L.
  1. Masaryk University
    753/5, Kamenice, Brno, Czech Republic, 62500
  2. O. V. Palladin Institute of Biochemistry, NAS of Ukraine
    9, Leontovycha Str., Kyiv, Ukraine, 01054

Abstract

Aim. This study is aimed at investigation of the CIN85 effect on osteosarcoma (OS) cells collagen adhesion and invasion. Conclusions. Our results demonstrate that increased CIN85 expression in osteosarcoma cells is associated with elevated collagen adhesion and invasion and may thereby contribute to metastasis.
Keywords: osteosarcoma, CIN85, invasion, adhesion, collagen
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