Biopolym. Cell. 1988; 4(6):290-297.
Cell Biology
Species and tissue-specific variations in distribution of mammalian tryptophanyl-tRNA synthetase: an abnormal high content in bovine pancreas
1Favorova O. O., 1Zargarova T. A., 2Rukosuev V. S., 1Beresten S. F.
  1. Institute of Molecular Biology, Academy of Sciences of the USSR
    Moscow, USSR
  2. Research Institute of Experimental Cardiology, National Cardiological Research Centre, Academy of Medical Sciences of the USSR
    Moscow, USSR


The content of tryptophanyl-tRNA synthetase has been determined in human, bovine, rat and rabbit liver and pancreatic extracts by direct radioimmunoblotting with 125I-labelled monoclonal antibody. It was in bovine but not in other pancreas that the unusually high amount of tryptophanyl-tRNA synthetase was estimated (about 0.2 %). According to the indirect immunofluorescent method, bovine tryptophanyl-tRNA synthetase is located in exocrinic part of the pancreatic gland.


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