Biopolym. Cell. 2017; 33(2):81-91.
http://dx.doi.org/10.7124/bc.000946
Reviews
Dependence of DNA persistence length on ionic conditions
1Zarudnaya M. I., 1Potyahaylo A. L., 1Hovorun D. M.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680

Abstract

DNA functioning requires both compaction for packaging into chromatin or virus particles and accessibility for looping to control gene expression. The persistence length (P), closely related to the bending rigidity of double-stranded DNA, is highly relevant to these processes. In spite of numerous experimental and theoretical studies, a general agreement on the dependence of DNA persistence length on salt concentration has not been established and clear understanding about the fundamental forces responsible for DNA stiffness is still lacking. Here we describe a dependence of P vs Na+ concentration based on several studies and discuss the impact of different factors, including DNA G- and A-tracts, on DNA persistence length.
Keywords: DNA, persistence length, effective diameter, G-tracts, A-tracts
Full text: (PDF, in English)

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